Extracurricular laboratory: Synthetic route of 3-Amino-5-bromopyridine-2-carboxylic Acid

The synthetic route of 870997-85-6 has been constantly updated, and we look forward to future research findings.

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 870997-85-6, name is 3-Amino-5-bromopyridine-2-carboxylic Acid, the common compound, a new synthetic route is introduced below. Quality Control of 3-Amino-5-bromopyridine-2-carboxylic Acid

To a 100 mL round bottom flask, 3-amino-5-bromo-pyridine-2-carboxylic acid (1 g, 0.0046 mol) and urea (27.8 g, 0.4629 mol) were added. The reaction mixture was stirred at 200 C. for 2.5 hours. The reaction mixture was cooled, water was added and the mixture was stirred to provide a precipitate. The precipitate was filtered and dried to provide the title compound (1 g, 91%). This material was taken to the next step without further purification.

The synthetic route of 870997-85-6 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Endo Pharmaceuticals Inc.; Smith, Roger Astbury; Venkatesan, Aranapakam; Bejugam, Mallesham; Hoshalli, Subramanya; Nanduri, Srinivas; US2014/38952; (2014); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem