Adding a certain compound to certain chemical reactions, such as: 1173081-96-3, 3-(Aminomethyl)-4,6-dimethylpyridin-2(1H)-one hydrochloride, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, SDS of cas: 1173081-96-3, blongs to pyridine-derivatives compound. SDS of cas: 1173081-96-3
General procedure: To a solution of indole derivatives (1 mmol), EDCI (0.29 g, 1.5 mmol), HOBt (0.20 g, 1.5 mmol) indry dichloromethane (10 mL) Et3N (0.76 g, 5 mmol) was added and the mixture was stirred at roomtemperature for 30 min. Then, the corresponding pyridone derivatives (1 mmol) was added, and theresulting mixture was reacted at room temperature for indicated time while monitoring by TLC. Whenthe reaction was complete the reaction mixture was poured into water, extracted with dichloromethane(15 x 3 mL), and washed with water (3 x 15 mL) and brine (15 mL). The organic solution was driedwith anhydrous sodium sulfate, filtered and evaporated under reduced pressure. The solid residuewas purified by column chromatography on silica gel.
The synthetic route of 1173081-96-3 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Chen, Guoliang; Du, Fangyu; Sun, Wenjiao; Wang, Lihui; Wu, Chunfu; Yang, Cheng; Zhou, Qifan; Molecules; vol. 25; 9; (2020);,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem