Application of 169833-70-9, Adding some certain compound to certain chemical reactions, such as: 169833-70-9, name is 6-Bromo-2-chloropyridin-3-amine,molecular formula is C5H4BrClN2, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 169833-70-9.
31.4 g 6-bromo-2-chloro-pyridin-3-amine (151.3 mmol) was dissolved in 200 ml glacialacetic acid, 15 mL acetic anhydride (158.9 mmol) was added to this solution dropwise and the reaction mixture was stirred at room temperature until no further conversion was observed. The reaction mixture was concentrated under reduced pressure. The residue was dissolved in ethyl acetate and the organic phase was washed with 10% aqueous K2C03 and brine. Following drying over Na2SO4 removal of the solvents under reduced pressure gaveN-(6-bromo-2-chloro-3 -pyridyl)acetamide.HPLC-MS: (M-H) = 247.0; 249.0
According to the analysis of related databases, 169833-70-9, the application of this compound in the production field has become more and more popular.
Reference:
Patent; LES LABORATOIRES SERVIER; VERNALIS (R&D) LIMITED; BALINT, Balazs; KOTSCHY, Andras; SIPOS, Melinda; WEBER, Csaba; FOLOPPE, Nicolas; WALMSLEY, David; BURBRIDGE, Michael, Frank; CRUZALEGUI, Francisco Humberto; (109 pag.)WO2017/55530; (2017); A1;,
Pyridine – Wikipedia,
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