Brief introduction of 1,1′-Thiocarbonylbis(pyridin-2(1H)-one)

According to the analysis of related databases, 102368-13-8, the application of this compound in the production field has become more and more popular.

Reference of 102368-13-8, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 102368-13-8, name is 1,1′-Thiocarbonylbis(pyridin-2(1H)-one). This compound has unique chemical properties. The synthetic route is as follows.

EXAMPLE 2 5-(4-Isothiocyanatophenyl)-10,15,20-tris(4-pyridyl)porphyrin To a stirred solution of 5 (100 mg, 0.158 mmol) in freshly distilled dichloromethane (20 mL) was added 1,1′-thiocarbonyldi-2(1H)-pyridone (320 mg, 1.38 mmol). The reaction was allowed to proceed under argon for 4 hours at room temperature. Excess solvent was evaporated in vacuo to yield a crude purple solid. The solid was dissolved in a minimal amount of chloroform and purified by flash chromatography (silica, eluent: CHCl3MeOH, 49:1). Relevant fractions were combined, dried (Na2SO4) and evaporated in vacuo to yield the above compound as a purple solid (104 mg, 97.5%); Rf=0.57 (silica, CHCl3/MeOH, 49:1); mp>350 C. decomp.; 1H NMR [270 MHz, CDCl3] delta-2.91 (2H, br s, NH), 7.65 (2H, m, J=8 Hz, 5-Ar-3,5-H), 8.15-8.21 (8H, m (overlapping), 10, 15, 20-Py-2,6-H & 5-Ar-2,6-H), 8.67 (8H, br s, beta-H), 9.06 (6H, m, J=5 Hz, 10, 15, 20-Py-3,5-H); 13C NMR [67.5 M, CDCl3]delta 117.4, 117.6, 119.7, 124.7, 129.3, 131.6, 135.4, 136.9, 140.6, 148.4, 149.8; UV-vis (CH2Cl2) lambdamax 417, 514, 548, 587, 643 nm; HRMS (ES) m/z calc’d for C42H26N8S (M+H) 675.2079, found 675.2078.

According to the analysis of related databases, 102368-13-8, the application of this compound in the production field has become more and more popular.

Reference:
Patent; Boyle, Ross William; Clarke, Oliver James; Sutton, Jonathan Mark; Greenman, John; US2003/203888; (2003); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem