Application of 55304-73-9

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,55304-73-9, its application will become more common.

Synthetic Route of 55304-73-9, Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 55304-73-9, name is 2,6-Dichloro-3-formylpyridine. A new synthetic method of this compound is introduced below.

2,6-Dichloronicotinaldehyde (500 mg, 2.84 mmol) was diluted with dimethylamine (3125 muL, 6.25 mmol) and heated to 500C. After stirring for 3 hours, the reaction was loaded onto a silica gel column and eluted with 5% ethyl acetate/hexanes to 50% ethyl acetate/hexanes to yield 6-chloro-2-(dimethylamino)nicotinaldehyde (155 mg, 0.840 mmol, 29.6 % yield).

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,55304-73-9, its application will become more common.

Reference:
Patent; ARRAY BIOPHARMA INC.; COOK, Adam; HUNT, Kevin, W.; DELISLE, Robert Kirk; ROMOFF, Todd; CLARK, Christopher, T.; KIM, Ganghyeok; CORRETTE, Christopher, P.; DOHERTY, George, A.; BURGESS, Laurence, E.; WO2010/75200; (2010); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem