Extracurricular laboratory: Synthetic route of 74976-31-1

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 74976-31-1, 6-Chloro-1H-pyrrolo[3,2-c]pyridine.

Related Products of 74976-31-1, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 74976-31-1, name is 6-Chloro-1H-pyrrolo[3,2-c]pyridine. This compound has unique chemical properties. The synthetic route is as follows.

6-chloro-i H-pyrrolo[3,2-c]pyridine (100 mg) and 2-bromopyrimidine (83 mg) was taken in Dioxane (3 ml) along with K3P04 (300 mg), diaminocyclohexane (ii mg) and Cul (6 mg). The reaction mixture was purged with Nitrogen and heated tol 10 00 for 1.2 hrs in microwave. The reaction mass was quenched with the addition of water and extracted with ethyl acetate. The ethyl acetate layer was dried and concentrated under reduced pressure to obatained the crudeproduct. The crude product was purified using silica gel column chromatography to obtaine pure product (80 mg).

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 74976-31-1, 6-Chloro-1H-pyrrolo[3,2-c]pyridine.

Reference:
Patent; BASF SE; VYAS, Devendra; VALLINAYAGAM, Ramakrishnan; SHINDE, Harish; SAMBASIVAN, Sunderraman; ADISECHAN, Ashokkumar; WACH, Jean-Yves; (91 pag.)WO2017/45955; (2017); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem