Reference of 13600-42-5, In the chemical reaction process,reaction time,type of solvent,can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product.An updated downstream synthesis route of 13600-42-5 as follows.
500 mL round bottom flask, 79.6 g (330 mmo 1) of 2,6-dichloro-3-cyano-4-(trifluoromethyl)pyridine concentrated sulfuric acid 400 grams heated to 100 degrees with stirring l h, after the reaction was added to the water to precipitate a solid, filtered and washed, dried to give a white solid 77 grams, yield 90.09%.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,13600-42-5, its application will become more common.
Reference:
Patent; Hebei Lan Tai Chemical Technology Co., Ltd.; Guo Ming; Meng Shuiqiang; Tian Penghui; Hou Jianjun; (14 pag.)CN107382848; (2017); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem