Synthetic Route of 18653-75-3, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 18653-75-3, name is 2-(1H-Imidazol-2-yl)pyridine. This compound has unique chemical properties. The synthetic route is as follows.
General procedure: To a mixture of 1.45 g (10 mmol) of 2-pyridyl-1H-imidazole, 0.62 g (11 mmol) of powdered KOH, and 10 mL of ethylene glycol dimethyl ether was added dropwise 0.68 g (11 mmol) of methyl iodide with vigorous stirring at 3-5 C, maintaining the reaction temperature no higher than 8 C. The mixture was stirred at this temperature for 0.5 h, and then poured into 100 mL of water. The reaction product was filtered off or extracted with chloroform (2×50 mL). The extract was dried over calcium chloride, chloroform was distilled off. The residue was extracted with hot hexane (3×50 mL) and evaporated to give the corresponding 1-methyl-2-pyridyl-1H-imidazole.
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 18653-75-3, 2-(1H-Imidazol-2-yl)pyridine.
Reference:
Article; El?chaninov; Aleksandrov; Klushin; Russian Journal of General Chemistry; vol. 86; 7; (2016); p. 1581 – 1583; Zh. Obshch. Khim.; vol. 86; 7; (2016); p. 1102 – 1105,3;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem