Adding a certain compound to certain chemical reactions, such as: 5632-81-5, 2-Chloropyridine-3,5-diamine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 5632-81-5, blongs to pyridine-derivatives compound. COA of Formula: C5H6ClN3
REFERENCE EXAMPLE 18 Synthesis of ethyl 3-[(5-amino-6-chloropyridin-3-yl)amino]-2-(3-chloro-2,4,5-trifluorobenzoyl)acrylate To 1.4 g of ethyl 3-chloro-2,4,5-trifluorobenzoyl-acetate were added 1.5 g of acetic anhydride and 1.5 g of triethyl orthoformate, and the mixture was heated under reflux for 2 hours. The solvent was distilled off, and toluene was added to the residue for azeotropic distillation. 3 ml of chloroform was added to the half of the residue, and a solution of 360 mg of 3,5-diamino-2-chloropyridine in 3 ml ethanol was added dropwise to the mixture at room temperature and the mixture was stirred at room temperature for 30 minutes. The solvent was distilled off, and the residue was purified by column chromatography to obtain 200 mg of the title compound.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,5632-81-5, its application will become more common.
Reference:
Patent; Wakunaga Pharmaceuticals Co., Ltd.; US5998436; (1999); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem