As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 1737-93-5, name is 3,5-Dichloro-2,4,6-trifluoropyridine, molecular formula is C5Cl2F3N, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below. Safety of 3,5-Dichloro-2,4,6-trifluoropyridine
S2.The above solution containing dichlorotrifluoropyridine was cooled to 10 C,And slowly dropping 30wt% aqueous ammonia at 10 C, the reaction was detected by TLC, to be dichloro-trifluoro pyridine reaction was complete,The reaction was stopped and a white solid was isolated as the desired drug intermediate (95.3% yield).
With the rapid development of chemical substances, we look forward to future research findings about 1737-93-5.
Reference:
Patent; Chongqing Huage Biochemical Co., Ltd.; He Xiaoqiang; Chen Zhizhong; Zhang Chunhua; Gu Fuhai; Wu Chengli; Yang Xinyao; (8 pag.)CN107311924; (2017); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem