As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 85838-94-4, name is tert-Butyl 5,6-dihydropyridine-1(2H)-carboxylate, molecular formula is C10H17NO2, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below. HPLC of Formula: C10H17NO2
To a solution of tert-butyl5,6-dihydropyridine-1(2H)-carboxylate (0.3627 g, 1.979 mmol) in CH2Ch (5 ml) at ooc was5 added a solution of mCPBA (0.53 g, 3.07 mmol) in CH2Cb (5 ml). The resulting reactionmixture was allowed to warm to rt and stirred over the weekend. The reaction was partitionedbetween EtOAc and 5% Na2S20 3. After separation of layers, the organic layer was washed withsat. NaHC03. brine, dried over anhydrous MgS0 4, filtered and concentrated to give the titlecompound as colorless oil.
With the rapid development of chemical substances, we look forward to future research findings about 85838-94-4.
Reference:
Patent; MERCK SHARP & DOHME CORP.; CHOBANIAN, Harry; PIO, Barbara; GUO, Yan; DING, Fa-Xiang; DONG, Shuzhi; WALSH, Shawn, P.; JIANG, Jinlong; KIM, Dooseop; WO2015/95097; (2015); A2;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem