07/9/2021 News A new synthetic route of 14294-11-2

At the same time, in my other blogs, there are other synthetic methods of this type of compound,14294-11-2, 1-(Pyridin-2-yl)thiourea, and friends who are interested can also refer to it.

Adding a certain compound to certain chemical reactions, such as: 14294-11-2, 1-(Pyridin-2-yl)thiourea, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, name: 1-(Pyridin-2-yl)thiourea, blongs to pyridine-derivatives compound. name: 1-(Pyridin-2-yl)thiourea

General procedure: Arylthiourea 2 (1 mmol) was added to a solution (in case of 1a) or suspension (for 1b,c) of 3-substituted 1,2,4-triazine 1 (1 mmol) in acetic anhydride. The reaction mixture was stirred at room temperature for 7-27 h. The precipitate obtained was filtered and washed with a small amount of acetic anhydride, diethyl ether and dried in air. For the analytical data, see Online Supplementary Materials.

At the same time, in my other blogs, there are other synthetic methods of this type of compound,14294-11-2, 1-(Pyridin-2-yl)thiourea, and friends who are interested can also refer to it.

Reference:
Article; Mochulskaya, Nataliya N.; Slepukhin, Pavel A.; Charushin, Valery N.; Kodess, Mikhail I.; Mendeleev Communications; vol. 26; 5; (2016); p. 375 – 377;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem