Adding a certain compound to certain chemical reactions, such as: 5346-38-3, Pyridine-2-carbothioamide, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 5346-38-3, blongs to pyridine-derivatives compound. Product Details of 5346-38-3
To a solution of 2-Bromo-1-(4-nitro-phenyl)-propan-1-one (6.13 g, 23.75 mmol) in absolute EtOH (200 ml) was added pyridine-2-carbothioic acid amide (3.28 g, 23.75 mmol). The mixture was heated to reflux for 2 h, after which it was concentrated to dryness, and the resulting solid was filtered and washed with Et2O to provide 2-[5-Methyl-4-(4-nitro-phenyl)-thiazol-2-yl]-pyridine (6.08 g, 85%) as a solid.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,5346-38-3, its application will become more common.
Reference:
Patent; Alam, Muzaffar; Du Bois, Daisy Joe; Hawley, Ronald Charles; Kennedy-Smith, Joshua; Minatti, Ana Elena; Palmer, Wylie Solang; Silva, Tania; Wilhelm, Robert Stephen; US2011/71150; (2011); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem