Adding a certain compound to certain chemical reactions, such as: 58530-53-3, 2,4-Dibromopyridine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Application In Synthesis of 2,4-Dibromopyridine, blongs to pyridine-derivatives compound. Application In Synthesis of 2,4-Dibromopyridine
Preparation of 4-bromo-2-phenylpyridine Into a 500 mL round-bottomed flask was placed 2,4-dibromopyridine (9.90 g, 41.8 mmol), phenylboronic acid (5.10 g, 41.8 mmol), and potassium carbonate (11.55 g, 84 mmol) in DME (100 mL). The reaction mixture was diluted with water (40 mL). This was degassed for 30 minutes and Pd(PPh3)4, (0.483 grams, 0.418 mmol) was added and the reaction was stiffed at reflux for 22 hours. The mixture was diluted with brine and ethyl acetate. The organic layer was washed with water, dried and adsorbed onto Celite and chromatographed on a 400 gram column eluted with 0-5% ethyl acetate in hexane giving the desired product (5.30 g, 54%) as clear colorless oil.
The synthetic route of 58530-53-3 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Universal Display Corporation; Beers, Scott; Xia, Chuanjun; Layek, Suman; Wendt, Harvey; US2014/8617; (2014); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem