In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 1603-41-4, name is 2-Amino-5-methylpyridine, the common compound, a new synthetic route is introduced below. Recommanded Product: 1603-41-4
3.40 mL of 50% sulfuric acid (v / v) was added to a 25 mL reaction flask followed by the addition of 1.00 g (10 mmol) of 2-amino-5-methylpyridine (Compound 1), the ice salt bath was cooled to below 10 C, After a few minutes, the reaction solution became milky white; and then slowly slowly adding 1.72 g (25 mmol) of a mixture of NaNO2 and 3 mL of H2O to form a brownish-colored irritating odor gas, and the reaction solution Into a pale yellow, with 10% dilute sulfuric acid to adjust the pH to 7-8, reflux stirring reaction about 20min, spin off most of the water, to which the appropriate amount of 300 mesh silica gel, spin dry, into the glass sand core funnel, The ester was filtered and the filtrate was spin-dried to obtain the crude product (Compound 3) which was used in the next step without purification.
The synthetic route of 1603-41-4 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Sichuan University; Yin, Shu-Fan; Li, Yong; Cao, Tingting; Yang, Ziyao; (16 pag.)CN105998016; (2016); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem