Application of 1658-42-0, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.1658-42-0, name is Methyl 2-(pyridin-2-yl)acetate, molecular formula is C8H9NO2, molecular weight is 151.16, as common compound, the synthetic route is as follows.
Example 6 1-Adamantan-2-yl-3-cyclopropyl-4-pyridin-2-yl-1,3-dihydro-imidazol-2-one Step A1 Cyclopropylamino-pyridin-2-yl-acetic acid methyl ester; This material was obtained in analogy to example 4, step A] from alpha-bromo-pyridin-2-yl-acetic acid methyl ester (1.0 g, CAS 52458-81-8, made by bromination of pyridine-2-yl-acetic acid methyl ester according to Tetrahedron, 58, 2002, 10113-10126) and cyclopropylamine (372 mg) to cyclopropylamino-pyridin-2-yl-acetic acid methyl ester as a light yellow liquid (515 mg). MS (ESI): 206.9 (MH+).
Statistics shows that 1658-42-0 is playing an increasingly important role. we look forward to future research findings about Methyl 2-(pyridin-2-yl)acetate.
Reference:
Patent; Ackermann, Jean; Amrein, Kurt; Hunziker, Daniel; Kuhn, Bernd; Mayweg, Alexander V.; Neidhart, Werner; Takahashi, Tadakatsu; US2008/103183; (2008); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem