Related Products of 7584-05-6, Adding some certain compound to certain chemical reactions, such as: 7584-05-6, name is 3-Methylisonicotinonitrile,molecular formula is C7H6N2, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 7584-05-6.
To a stirred solution of 3-methylisonicotinonitrile (5.00 g, 42.30 mmol) in DCM(100 mL)was added 3chioroperoxybenzoic acid (14.61 g, 85.00 nimol) at 0 C and stirred at ambienttemperature for 16 h. The reaction mixture was diluted with water (50 mL), basified with 10 % NaHCO3 and extracted with ethyl acetate (2 x 75 mL). The combined organic layers were washed with brine (50 mL), dried over sodium sulfate and evaporated under reduced pressure to obtain Intermediate 24A (3.50 g, 61.30%) as a pale yellow solid. ?HNIVR (400 MHz, DMSOd6) oe ppm 2.38 (s, 3 H), 7.84 7.85 (d, .1= 6.8 Hz, 1 H), 8.21 8.23 (dd, J= 1.2 Hz, 6.8 Hz, IH),8.41 (s, 1H). LCMS MethodD): retention time 0.44 mm, [M+H1 135.2.
According to the analysis of related databases, 7584-05-6, the application of this compound in the production field has become more and more popular.
Reference:
Patent; BRISTOL-MYERS SQUIBB COMPANY; GUNAGA, Prashantha; BHIDE, Rajeev S.; BORA, Rajesh Onkardas; PANDA, Manoranjan; YADAV, Navnath Dnyanoba; PRIESTLEY, Eldon Scott; RICHTER, Jeremy; (321 pag.)WO2018/93569; (2018); A1;,
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