Shestopalov, AM; Rodinovskaya, LA; Zubarev, AA; Nesterov, VN; Ugrak, BI; Dutova, TY in [Shestopalov, Anatoliy M.; Rodinovskaya, Lyudmila A.; Zubarev, Andrey A.; Ugrak, Bogdan I.; Dutova, Tatyana Ya.] Russian Acad Sci, ND Zelinsky Inst Organ Chem, Leninsky Prospekt 47, Moscow 119991, Russia; [Nesterov, Vladimir N.] Univ North Texas, Dept Chem, Denton, TX 76203 USA published Synthesis and domino reactions of polymethylene-3-cyanopyridine-2(1H)-thiones in 2020.0, Cited 30.0. Formula: C6H5NO. The Name is 3-Pyridinecarboxaldehyde. Through research, I have a further understanding and discovery of 500-22-1.
A new and facile three-component method was developed for the synthesis of polymethylene-3-cyanopyridine-2(1H)-thiones by the domino Knoevenagel -> Michael -> heterocyclization -> dehydrogenation reaction from cycloalkanones, cyanothioacetamide, and polymethoxy-substituted benzaldehydes. The final dehydrogenation step was found to involve arylidenecyanothioacetamide. The resulting pyridinethiones and 4-chloroacetoacetic ester were introduced into the domino S(N)2 -> Thorpe-Ziegler -> Guareschi-Thorpe reaction to synthesize tetracyclic dipyridothiophenes. Starting from these compounds, 8,9-polymethylenepyranothienodipyridines were also synthesized by the domino Knoevenagel -> Michael -> hetero-Thorpe-Ziegler reaction. Furthermore, a method for the synthesis of thienodipyridine annulated to the steroid skeleton is proposed.
Formula: C6H5NO. About 3-Pyridinecarboxaldehyde, If you have any questions, you can contact Shestopalov, AM; Rodinovskaya, LA; Zubarev, AA; Nesterov, VN; Ugrak, BI; Dutova, TY or concate me.
Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem