Recently I am researching about C-H BONDS; OLEFIN SYNTHESIS; ENANTIOSELECTIVE SYNTHESIS; INTERNAL ALKYNES; ALDEHYDES; ALKENYLATION; CARBANIONS; 1,3-DIENES; ALCOHOLS; ALKENES, Saw an article supported by the Killam Fellowship of the Canadian Council of Arts; China Scholarship CouncilChina Scholarship Council. Safety of 3-Pyridinecarboxaldehyde. Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Yu, L; Lv, LY; Qiu, ZH; Chen, ZP; Tan, Z; Liang, YF; Li, CJ. The CAS is 500-22-1. Through research, I have a further understanding and discovery of 3-Pyridinecarboxaldehyde
We have developed an unprecedented Pd-catalyzed formal hydroalkylation of alkynes with hydrazones, which are generated in situ from naturally abundant aldehydes, as both alkylation reagents and hydrogen donors. The hydroalkylation proceeds with high regio- and stereoselectivity to form (Z)-alkenes, which are more difficult to generate compared to (E)-alkenes. The reaction is compatible with a wide range of functional groups, including hydroxy, ester, ketone, nitrile, boronic ester, amine, and halide groups. Furthermore, late-stage modifications of natural products and pharmaceutical derivatives exemplify its unique chemoselectivity, regioselectivity, and synthetic applicability. Mechanistic studies indicate the possible involvement of Pd-hydride intermediates.
Safety of 3-Pyridinecarboxaldehyde. About 3-Pyridinecarboxaldehyde, If you have any questions, you can contact Yu, L; Lv, LY; Qiu, ZH; Chen, ZP; Tan, Z; Liang, YF; Li, CJ or concate me.
Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem