73583-37-6, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 73583-37-6, name is 4-Bromo-2-chloropyridine. This compound has unique chemical properties. The synthetic route is as follows.
4-Bromo-2-chloropyridine V (50 g, 260 mmol, 1.0 equiv ¡¤) was dispersed in 96 ml of 80% hydrazine hydrate (4.794mol, 12 equiv.), And the reaction was performed in an oil bath at 60 C for 48 hours. TLC showed the reaction At the end, the pH of 2 W sodium hydroxide solution was adjusted to 12, EA / THF (2: 1) was extracted, and the organic phase was concentrated to obtain 31.3 g of a pale yellow solid, namely 2-chloro-4-hydrazinopyridine I, with a yield of 84 %.
Statistics shows that 73583-37-6 is playing an increasingly important role. we look forward to future research findings about 4-Bromo-2-chloropyridine.
Reference:
Patent; Nanjing He Ju Pharmaceutical Co., Ltd.; Pan Guojun; (6 pag.)CN110041252; (2019); A;,
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