Recommanded Product: Ethyl nicotinate. In 2019 TALANTA published article about SOLID-PHASE MICROEXTRACTION; SIMULTANEOUS QUANTIFICATION; NICOTINE METABOLITES; EXTRACTION; COTININE; URINE; NITROSAMINES; CAPILLARY; HAIR; EXPOSURE in [Wu, Fangling; Ding, Chuan-Fan] Ningbo Univ, Sch Mat Sci & Chem Engn, Inst Mass Spectrometry, Ningbo 315211, Zhejiang, Peoples R China; [Wu, Fangling; Yang, Shutong; Wang, Liang; Wei, Wanghui; Ding, Chuan-Fan] Fudan Univ, Dept Chem, Shanghai 200438, Peoples R China in 2019, Cited 40. The Name is Ethyl nicotinate. Through research, I have a further understanding and discovery of 614-18-6.
Herein, we realized the simultaneous online detection of six tobacco alkaloids (TM) by in-tube solid-phase microextraction (In-tube SPME) coupled with mass spectrometry by a rapid, sensitive, and matrix effect-free method requiring no chromatographic separation and only minimal sample pre-treatment. A poly (N-isopropylacrylamide-co-divinylbenzene-co-N, N’-methylenediacrylamide) [Poly (NIPAAm-co-DVB-co-MBAA)] monolithic column was designed according to the chemical structures of selected TM and used as an extraction medium engaging in hydrophobic, pi-pi, and hydrogen bonding interactions with analytes, allowing them to be effectively extracted. A number of important parameters were systematically optimized to achieve maximal extraction efficiency. The ion intensity of the TM signals obtained by in-tube SPME-MS were higher than the direct MS mode by about 400 folds with the signal-to-noise ratio improved by 2-7 folds. The detection limits of the six TM were determined as 1.99-4.06 ng g(-1), with good linearity with correlation coefficients exceeding 0.99 obtained under optimal extraction conditions. Besides, TA recoveries in cigarette tobacco spiked at three concentration levels were in the range of 76.4-100.2%, and the corresponding RSDs (n = 5) were obtained as 4.32-7.16%. The extraction performance of the poly (NIPAAm-co-DVB-co-MBAA) monolithic column was well reproducible, with intra- or inter-day precision RSDs determined not to exceed 7.38%. Finally, no marked matrix effects were observed when the developed method was applied to the analysis of both high-abundance and trace level TM in practical samples, and the above technique was therefore concluded to be well suited for the detection of TAs in cigarette tobacco or other products.
Recommanded Product: Ethyl nicotinate. About Ethyl nicotinate, If you have any questions, you can contact Wu, FL; Yang, ST; Wang, L; Wei, WH; Ding, CF or concate me.
Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem