I found the field of Chemistry very interesting. Saw the article Design, Synthesis, Molecular Docking and Biological Evaluation of 1-(benzo[d]thiazol-2-ylamino)(phenyl)methyl)naphthalen-2-ol Derivatives as Antiproliferative Agents published in 2019.0. Recommanded Product: 500-22-1, Reprint Addresses Nameta, B; Chavali, M (corresponding author), Vignans Fdn Sci Technol & Res Guntur, Dept Sci & Humanities, Div Chem, Guntur, India.; Reddy, BVS (corresponding author), Indian Inst Chem Technol, CSIR, Ctr Semiochem, Hyderabad 500007, Andhra Pradesh, India.. The CAS is 500-22-1. Through research, I have a further understanding and discovery of 3-Pyridinecarboxaldehyde
A class of 1-((benzo[d]thiazol-2-ylamino)(phenyl)methyl)naphthalen-2-ol derivatives (4a-t) has been synthesized in good yields through a three component coupling reaction. The newly synthesized compounds were evaluated for their in vitro antiproliferative activity against five cell lines such as DU145 (human prostate cancer), MDA-MB-B231 (human breast cancer), SKOV3 (human ovarian cancer), B16-F10 (mouse skin melanoma) and CHO-K1 (Chinese hamster ovary cells), a non-cancerous cell line. In vitro inhibitory activity indicates that compounds 4a, 4b, 4c, 4d, 4g, 4j, and 4o exhibited potent anti-proliferative behavior. Among them, compounds 4g, 4j and 4o found to be the most active members exhibiting remarkable growth inhibitory activity. Molecular docking facilitates to investigate the probable binding mode and key active site interactions in tubulins alpha and beta proteins. The docking results are complementary to experimental results.
Recommanded Product: 500-22-1. About 3-Pyridinecarboxaldehyde, If you have any questions, you can contact Jonnala, S; Nameta, B; Chavali, M; Bantu, R; Choudante, P; Misra, S; Sridhar, B; Dilip, S; Reddy, BVS or concate me.
Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem