Recently I am researching about COORDINATION CHEMISTRY; FLUORESCENT SENSORS; CU(II) COMPLEXES; SYNAPTIC ZINC; MECHANISM; RUTHENIUM(II); VITAMIN-B-6; COPPER(II); INDUCTION; LIGANDS, Saw an article supported by the CSIRCouncil of Scientific & Industrial Research (CSIR) – India; IIEST, Shibpur. Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Mondal, S; Chakraborty, M; Mondal, A; Pakhira, B; Mukhopadhyay, SK; Banik, A; Sengupta, S; Chattopadhyay, SK. The CAS is 65-22-5. Through research, I have a further understanding and discovery of 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride. HPLC of Formula: C8H10ClNO3
Herein we report, a mononuclear, highly fluorescent zinc(ii) complex Zn(L)(N-3)(H2O) (1) that was prepared by an easy one pot method, in which the tridentate Schiff base ligand (E)-4-((2-(dimethylamino)ethylimino)methyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol (HL) was generated in situ. The compound is characterized by various spectroscopic techniques, and its structure was determined by single crystal X-ray diffraction studies. DFT calculations were used to understand the electronic structures of the ligand and the complex, and TD-DFT calculations were performed to interpret the nature of the electronic transitions observed in their UV-vis spectra. In the complex, Zn(II) is found to be penta-coordinated with one azide ligand, an aqua ligand and a monoanionic tridentate N,N,O-donor ligand. In an aqueous methanol (1:9 by volume) solution, at the physiological pH (0.01 M Tris-HCl buffer, pH 7.4), compound 1 exhibits an intense greenish blue fluorescence (lambda(ex) 390 nm, lambda(em) 462 nm), whose intensity is about 17-fold stronger than that of the free ligand. Compound 1 is found to show significant DNA binding activity. The pyridoxal appended tridentate ligand can be used for the bio-imaging of Zn(II).
HPLC of Formula: C8H10ClNO3. About 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride, If you have any questions, you can contact Mondal, S; Chakraborty, M; Mondal, A; Pakhira, B; Mukhopadhyay, SK; Banik, A; Sengupta, S; Chattopadhyay, SK or concate me.
Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem