SDS of cas: 500-22-1. Kurva, M; Kerim, MD; Gamez-Montano, R; El Kaim, L in [Kurva, Mahanandaiah; Kerim, Mansour Dole; El Kaim, Laurent] Ecole Polytech, Inst Polytech Paris, Lab Synth Organ, CNRS,ENSTA Paris,UMR 7652, 828 Bd Marechaux, F-91128 Palaiseau, France; [Kurva, Mahanandaiah; Gamez-Montano, Rocio] Univ Guanajuato, Dept Quim, Noria Alta S-N, Guanajuato 36050, Gto, Mexico published Straightforward access to complex isoindolinones from the Ugi reaction of o-nitrobenzoic acid derivatives in 2019.0, Cited 36.0. The Name is 3-Pyridinecarboxaldehyde. Through research, I have a further understanding and discovery of 500-22-1.
The Ugi reaction of 2-nitrobenzoic acid derivatives has been used for a diversity oriented synthesis of complex isoindolinones via a SNAr reaction involving the peptidyl position. When the cyclization is triggered by strong bases such as potassium tert-butylate, the SNAr reaction is followed by a deamidification/oxidation sequence leading to 2-hydroxyisoindolinones. The latter may be further transformed into polycyclic fused isoindolinones via Pictet-Spengler type cyclization or O-alkylation/metathesis sequences.
SDS of cas: 500-22-1. About 3-Pyridinecarboxaldehyde, If you have any questions, you can contact Kurva, M; Kerim, MD; Gamez-Montano, R; El Kaim, L or concate me.
Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem