Discovery of 91-02-1

SDS of cas: 91-02-1. About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Yamada, M; Azuma, K; Yamano, M or concate me.

I found the field of Chemistry very interesting. Saw the article Highly Enantioselective Direct Asymmetric Reductive Amination of 2-Acetyl-6-Substituted Pyridines published in 2021.0. SDS of cas: 91-02-1, Reprint Addresses Yamada, M (corresponding author), Takeda Pharmaceut Co Ltd, Pharmaceut Sci, Proc Chem, Osaka 5320024, Japan.. The CAS is 91-02-1. Through research, I have a further understanding and discovery of Phenyl(pyridin-2-yl)methanone

A highly direct asymmetric reductive amination of a variety of ketone substrates, including 2-acetyl-6-substituted pyridines, beta-keto esters, beta-keto amides, and 1-(6-methylpyridin-2yl)propan-2-one, has been disclosed for the first time (94.6% to >99.9% ee). With ammonium trifluoroacetate as the nitrogen source, various chiral corresponding primary amines were prepared in excellent enantioselectivity and conversion in the presence of a commercially available and inexpensive chiral catalyst, Ru(OAc)(2){(S)-binap}, under 0.8 MPa of hydrogen gas pressure.

SDS of cas: 91-02-1. About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Yamada, M; Azuma, K; Yamano, M or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem