An article One-Pot, Tandem Wittig Hydrogenation: Formal C(sp(3))-C(sp(3)) Bond Formation with Extensive Scope WOS:000547468700059 published article about EMPLOYING STABILIZED YLIDES; LAPATINIB DERIVATIVES; ALDEHYDES; DESIGN; WATER in [Devlin, Rory; Jones, David J.; McGlacken, Gerard P.] Univ Coll Cork, Sch Chem, Cork T12 YN60, Ireland; [Devlin, Rory; Jones, David J.; McGlacken, Gerard P.] Univ Coll Cork, Analyt & Biol Chem Res Facil ABCRF, Cork T12 YN60, Ireland; [McGlacken, Gerard P.] Univ Coll Cork, Synth & Solid State Pharmaceut Ctr SSPC, Cork T12 YN60, Ireland in 2020.0, Cited 34.0. Computed Properties of C6H5NO. The Name is 3-Pyridinecarboxaldehyde. Through research, I have a further understanding and discovery of 500-22-1
A one-pot, tandem Wittig hydrogenation of aldehydes with stabilized ylides is reported, representing a formal C(sp(3))-C(sp(3)) bond construction. The tandem reaction operates under mild conditions, is high yielding, and is broad in scope. Chemoselectivity for olefin reduction is observed, and the methodology is demonstrated in the synthesis of lapatinib analogues and a formal synthesis of (+/-)-cuspareine. Early insights suggest that the chemoselectivity observed in the reduction step is due to partial poisoning of the catalyst, after step one, thus adding to the power of the one-pot procedure.
Welcome to talk about 500-22-1, If you have any questions, you can contact Devlin, R; Jones, DJ; McGlacken, GP or send Email.. Computed Properties of C6H5NO
Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem