An article Synthetic chloroinconazide compound exhibits highly efficient antiviral activity against tobacco mosaic virus WOS:000538878900002 published article about SALICYLIC-ACID; SYSTEMIC RESISTANCE; REGULATORY MECHANISMS; OXIDATIVE BURST; PLANT-VIRUSES; CUCUMBER; INDUCTION; DEFENSE; DERIVATIVES; TMV in [Wang, Xiangchuan; Wu, Lei; Gong, Weiwei; Hao, Chunyan; Cheng, Daoquan] Jingbo Agrochem Technol Co LED, Natl Ctr Enterprise Technol, Binzhou 256500, Peoples R China; [Lv, Xing; Xiang, Shunyu; Liu, Changyun; Yuan, Mengting; Win, HsuMyat; Xue, Yang; Sun, Xianchao] Southwest Univ, Coll Plant Protect, Chongqing 400716, Peoples R China; [Ma, Lisong] Australian Natl Univ, Res Sch Biol, Div Plant Sci, Canberra, ACT, Australia; [Ma, Lisong] Hebei Agr Univ, Coll Plant Protect, State Key Lab North China Crop Improvement & Regu, Baoding, Peoples R China in 2020.0, Cited 72.0. The Name is 3-Pyridinecarboxaldehyde. Through research, I have a further understanding and discovery of 500-22-1. Formula: C6H5NO
BACKGROUND Development of anti-plant-virus compounds and improvement of biosafety remain hot research topics in controlling plant viral disease. Tobacco mosaic virus (TMV) infects all tobacco species as well as many other plants worldwide and causes severe losses in tobacco production. To date, no efficient chemical treatments are known to protect plants from virus infection. Therefore, the search for a highly active antiviral compound with high efficacy in field application is required. RESULTS We reported the synthesis of a novel antiviral halogenated acyl compound Chloroinconazide (CHI) using tryptophan as a substrate and examined its anti-TMV activity. We found that CHI displayed the ability to strongly inhibit the infection of TMV on Nicotiana benthamiana via multiple mechanisms. We observed that CHI was able to impair the virulence of TMV by directly altering the morphological structure of virions and increasing the activity of anti-oxidative enzymes, resulting in reduced TMV-induced ROS production during infection of the plant. In addition, the expression of salicylic acid-responsive genes was significantly increased after CHI application. However, after application of CHI on SA-deficient NahG plants no obvious anti-TMV activity was observed, suggesting that the SA signaling pathway was required for CHI-induced anti-TMV activity associated with reduced infection of TMV. CHI exhibited no effects on plant growth and development. CONCLUSION The easily synthesized CHI can actively induce plant resistance against TMV as well as act on virus particles and exhibits high biosafety, which provides a potential for commercial application of CHI in controlling plant virus disease in the future.
Formula: C6H5NO. Welcome to talk about 500-22-1, If you have any questions, you can contact Lv, X; Xiang, SY; Wang, XC; Wu, L; Liu, CY; Yuan, MT; Gong, WW; Win, H; Hao, CY; Xue, Y; Ma, LS; Cheng, DQ; Sun, XC or send Email.
Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem