How did you first get involved in researching 3-Pyridinecarboxaldehyde

COA of Formula: C6H5NO. Welcome to talk about 500-22-1, If you have any questions, you can contact Secci, D; Carradori, S; Petzer, A; Guglielmi, P; D’Ascenzio, M; Chimenti, P; Bagetta, D; Alcaro, S; Zengin, G; Petzer, JP; Ortuso, F or send Email.

COA of Formula: C6H5NO. Recently I am researching about MONOAMINE-OXIDASE-B; HIGH-POTENCY; IN-VITRO; MAO; SCAFFOLD; DESIGN; AGENTS; IDENTIFICATION, Saw an article supported by the Progetto di Ricerca Ateneo La Sapienza (Italy) [C26A14AC5L]; POR FESR LAZIO 2014/2020 – REGIONE LAZIO – Avviso pubblico LIFE 2020. Published in TAYLOR & FRANCIS LTD in ABINGDON ,Authors: Secci, D; Carradori, S; Petzer, A; Guglielmi, P; D’Ascenzio, M; Chimenti, P; Bagetta, D; Alcaro, S; Zengin, G; Petzer, JP; Ortuso, F. The CAS is 500-22-1. Through research, I have a further understanding and discovery of 3-Pyridinecarboxaldehyde

A new series of 4-(3-nitrophenyl)thiazol-2-ylhydrazone derivatives were designed, synthesised, and evaluated to assess their inhibitory effect on the human monoamine oxidase (hMAO) A and B isoforms. Different (un)substituted (hetero)aromatic substituents were linked to N1 of the hydrazone in order to establish robust structure-activity relationships. The results of the biological testing demonstrated that the presence of the hydrazothiazole nucleus bearing at C4 a phenyl ring functionalised at the meta position with a nitro group represents an important pharmacophoric feature to obtain selective and reversible human MAO-B inhibition for the treatment of neurodegenerative disorders. In addition, the most potent and selective MAO-B inhibitors were evaluated in silico as potential cholinesterase (AChE/BuChE) inhibitors and in vitro for antioxidant activities. The results obtained from molecular modelling studies provided insight into the multiple interactions and structural requirements for the reported MAO inhibitory properties.

COA of Formula: C6H5NO. Welcome to talk about 500-22-1, If you have any questions, you can contact Secci, D; Carradori, S; Petzer, A; Guglielmi, P; D’Ascenzio, M; Chimenti, P; Bagetta, D; Alcaro, S; Zengin, G; Petzer, JP; Ortuso, F or send Email.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem