Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, Name: 2,6-Dichloropyridine2402-78-0, Name is 2,6-Dichloropyridine, SMILES is ClC1=CC=CC(Cl)=N1, belongs to pyridine-derivatives compound. In a article, author is Tahmasby, Maryam, introduce new discover of the category.
Pyrido triazin-nucleus synthesis and theoretical studies: 2,3,6-trioxo-8-aryl-1,3,4,6-tetrahydro-]2H[pyrido]1,2-b][1,2,4[triazin-7,9-dicarbonitryl derivatives
An efficient method for the synthesis of potentially biologically [2H]-pyrido [1,2-b]1,2,4-triazines derivatives is described via reaction of 1,6-diamino-2-oxo-4-phenyl-1,2-dihydropyridine-3,5-dicarbonitrile derivatives with oxalyl chloride in DMF in the presence of pyridine as a base. The intramolecular hydrogen bonding (IMHB) interactions have been investigated at M06-2X/6-311 ++ G(d,p) level of theory. The eight compounds (5a-h) characterized by geometries and energies. The Natural bond orbital (NBO) and quantum theory of atoms in molecules (QTAIM) were performed to explore the nature of the hydrogen bonding interactions in these compounds. The IMHB formed between the C = O and N-H groups. The theoretical calculations showed that the IMHB strength increases in the presence of electron-donor substituents. An opposite behavior was observed for electron-acceptor substituents. (c) 2020 Published by Elsevier B.V.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 2402-78-0. Name: 2,6-Dichloropyridine.
Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem