Chemistry is traditionally divided into organic and inorganic chemistry. The former is the study of compounds containing at least one carbon-hydrogen bonds. 51173-04-7, Name is 5-Fluoro-2-methoxypyridine, molecular formula is C6H6FNO, belongs to pyridine-derivatives compound, is a common compound. In a patnet, author is Vogelsang, Dennis, once mentioned the new application about 51173-04-7, Category: pyridine-derivatives.
Palladium Catalysed Acid-Free Carboxytelomerisation of 1,3-Butadiene with Alcohols Accessing Pelargonic Acid Derivatives Including Triglycerides under Selectivity Control
Palladium catalysed carboxytelomerisation of 1,3-butadiene with alcohols yields unsaturated C-9-pelargonic esters in an atom-economic and straightforward way. Although carboxytelomerisation is of current interest, limitations of applicable alcohol substrates have not been fully investigated. In here, we present the transfer of the catalytic system comprising palladium acetate and tri-n-butyl phosphine in pyridine to a broad variety of 20 alcohols with vast difference in nucleophilicity and sterical demands yielding the corresponding esters in a 100% atom economic manner. Effects of nucleophilicity and sterical demands were revealed for monoalcohols, di- and polyols. Whilst yields, chemoselectivity and E/Z-selectivity of the pelargonic acid derivatives were excellent with up to 99%, selectivity towards mono-, di- and triesters could be controlled successfully. Finally, the reaction profile of the carboxytelomerisation glycerol was uncovered, yielding up to 97% of industrially relevant unsaturated C-9-short chain fats.
We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 51173-04-7. The above is the message from the blog manager. Category: pyridine-derivatives.
Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem