In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 78427-26-6, name is 1-(4-Aminophenyl)pyridin-1-ium chloride, the common compound, a new synthetic route is introduced below. Recommanded Product: 1-(4-Aminophenyl)pyridin-1-ium chloride
To a 250 mL Erlenmeyer flask were added 14.6 g of l-(4-aminophenyl)pyridine-l-ium chloride (“PyCI”), 20 g deionized ice water, and 80 g of deionized water under stirring. After all PyCI solids were dissolved, 40 mL of 2M sodium nitrite was added to this solution, which was then put into an ice-water bath and cooled to [0062] In a separate 2L vessel, 22.89 g of N-(5-chloro-2-methoxyphenyl)-3-hydroxy-2-naphthamide (available from TCI as Naphthol AS-CA) was dissolved in a solution 37.5 mL of 2M NaOH and 250 ml of ethanol. The resulting solution was cooled to 5C. To this solution was added the diazo-PyCI solution dropwise with vigorous stirring over a time period of 40 min to 1 hour. Since the solution became very viscous during the addition period, another 200 mL of ethanol and 300 mL of methanol were added to ensure a good mixing. During the whole addition period, approximately 50 mL of 2M NaOH was added to the reaction mixture to maintain a pH > 12. The reaction mixture was allowed to warm back to room temperature gradually and then stirred at room temperature overnight. The resulting red precipitate was removed by filtration, washed with deionized water, and dried in the vacuum oven at 60C to yield 32.4 g of the Cationic Synergist I.
The synthetic route of 78427-26-6 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Cabot Corporation; Xu, Jinqi; (21 pag.)CN106062087; (2016); A;,
Pyridine – Wikipedia,
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