Electric Literature of 14294-11-2, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 14294-11-2, name is 1-(Pyridin-2-yl)thiourea, molecular formula is C6H7N3S, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
N-Pyridin-2-ylthiourea 51b (5 g; 35.9 mmol) and 2-(3-bromo-2-oxopropyl)-1H-isoindole-1,3 (2H)-dione (9.1 g; 32.26 mmol) were stirred in 500 ml of THF at RT for 2 h. The precipitate which had formed was filtered off and dried. 12.3 g of white solid; ESI-MS [M+H+]=337.05.
According to the analysis of related databases, 14294-11-2, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Abbott GmbH & Co. KG; US7105508; (2006); B1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem