A new synthetic route of 2-Chloro-N-(4′-chloro-[1,1′-biphenyl]-2-yl)nicotinamide

With the rapid development of chemical substances, we look forward to future research findings about 188425-85-6.

As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 188425-85-6, name is 2-Chloro-N-(4′-chloro-[1,1′-biphenyl]-2-yl)nicotinamide, molecular formula is C18H12Cl2N2O, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below. name: 2-Chloro-N-(4′-chloro-[1,1′-biphenyl]-2-yl)nicotinamide

For a 1 :1 co-crystal of boscalid and 4-hydroxy benzoic acid, 200,0 mg of boscalid, 80,4 mg of 4-hydroxi benzoic acid and 150 muIota of ethanol was grinded in a ball mill (Retsch Modell MM301 ) for 10 minutesby using 20 Hz. The crystalline product gave the PXRD in Figure 4 (table 6).

With the rapid development of chemical substances, we look forward to future research findings about 188425-85-6.

Reference:
Patent; BASF SE; SAXELL, Heidi, Emilia; ISRAELS, Rafel; SCHAeFER, Ansgar; BRATZ, Matthias; HOeFFKEN, Hans, Wolfgang; BRODE, Ingo; NAUHA, Elisa; NISSINEN, Maija; WO2011/54741; (2011); A2;,
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