The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 72716-87-1, name is 2-Methoxyisonicotinaldehyde. This compound has unique chemical properties. The synthetic route is as follows. Computed Properties of C7H7NO2
6-methoxypyridine-3-carbaldehyde (3 g (0.022 mol)), malonic acid (4.35 g (0.042 mol)), pyridine (15 mL), and piperidine (400 ul, 4 mmol) were mixed well, heated to 80-85 C. for 1 h and finally refluxed (110-115 C.) for an additional 3 h. The reaction mixture was poured into water and acidified with concentrated HCl. The precipitate obtained was filtered, and washed with cold water repeatedly. The residue was dissolved in NaOH, diluted, again acidified, the precipitate was collected washed with cold water and dried under high vacuum over P2O5 and used without further purifications. Yield=2.8 g.
With the rapid development of chemical substances, we look forward to future research findings about 72716-87-1.
Reference:
Patent; Prosetta Antiviral, Inc.; ATUEGBU, Andy; SOLAS, Dennis; HURT, Clarence R.; KITAYGORODSKYY, Anatoliy; (141 pag.)US2016/168100; (2016); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem