Reference of 175422-04-5, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 175422-04-5, name is 2,6-Dibromo-4-nitropyridine, molecular formula is C5H2Br2N2O2, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
P. 2, 6-Dibromo-pyridin-4-ylamine A solution of 15.3 G (54.3 MMOL) 2,6-dibromo-4-nitro-pyridine and 18.5 ml (271.5 MMOL) 25% aq. ammonia in 40 mi tetrahydrofurane was transferred to an autoclave and heated at 95 C for 2.5 h. After cooling to room temperature, the reaction was poured into water (200 mi) and extracted with dichloromethane (3 x 200 ML). The organic layers were dried over magnesium sulphate and concentrated in vacuo. The residue was crystallized from ethyl acetate/petroleum ether to afford 9.6 G (70%) of the title compound as a yellow solid. m. p. 184-186 C.
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 175422-04-5, 2,6-Dibromo-4-nitropyridine.
Reference:
Patent; ALTANA PHARMA AG; WO2005/26164; (2005); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem