Related Products of 697300-73-5, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.697300-73-5, name is 3-Bromo-5-iodopyridin-2-amine, molecular formula is C5H4BrIN2, molecular weight is 298.9071, as common compound, the synthetic route is as follows.
30 g of 3-bromo-5-iodopyridin-2-amine and 300 ml of ethanol were added1 g palladium / silica,First replace the air with nitrogen three times,And then replaced with hydrogen three times.Adjust the pressure of 0.05Mpa ~ 0.1Mpa,Temperature control at 20 ~ 30 , until the raw material reaction is complete.Filtration recovery catalyst,Concentrated part of the solvent,Add 300 ml of water,Then add 4.2 g of sodium hydroxide to neutralize,Cooled to 0 ~ 5 , filtered and dried.To give 16.8 g of 3-bromopyridin-2-amine,Yield 97%.
The chemical industry reduces the impact on the environment during synthesis 697300-73-5, I believe this compound will play a more active role in future production and life.
Reference:
Patent; Zhejiang Jiuzhou Pharmaceutical Co., Ltd.; Zheng, Hui; Luo, Lijun; Qiu, Zhichao; (5 pag.)CN106432068; (2017); A;,
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