624-28-2, A common compound: 624-28-2, name is 2,5-Dibromopyridine,molecular formula is C5H3Br2N, it can change the direction of chemical reaction, and react with certain compounds to generate new functional products. A new synthetic method of this compound is introduced below.
A) 5-Bromo-pyridine-2-yl-hydrazine [0213] A mixture of 2,5-dibromopyridine (44.2 g, 0.187 moles), hydrazine hydrate (55% by weight, 105.7 mL, 1.87 mol), poly(ethylene glycol) (187.0 mL), 2-butanol (37.3 mL) and water (187.0 mL) under nitrogen is refluxed gently for 29 hours. The mixture is cooled and stirred for 20 hours. To the resulting slurry, cold water (220.0 mL) is added. The slurry is stirred for an additional 30 minutes and filtered. The cake is washed with cold water (3¡Á) and dried in a vacuum-oven (40-45 C.) for 48 hours. The title compound (30.5 g, 87%) may be obtained as off-white flakes.
With the rapid development of chemical substances, we look forward to future research findings about 624-28-2.
Reference:
Patent; Pfizer Inc; US2004/87615; (2004); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem