Electric Literature of 94220-38-9, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 94220-38-9, name is 7-Chloro-5-methyl-1H-pyrazolo[4,3-b]-pyridine. This compound has unique chemical properties. The synthetic route is as follows.
EXAMPLE 1 7-(4-Cyanoanilino)-5-methyl-1H-pyrazolo[4,3-b]pyridine (E1) STR14 7-Chloro-5-methyl-1H-pyrazolo[4,3-b]pyridine (4 g, 0.024 mole) was heated at reflux under nitrogen with 4-aminobenzonitrile (9.44 g, 0.08 mole) in dry xylene (25 ml) for 8 h. The resulting yellow crystalline solid was collected and washed repeatedly with ethyl acetate. This solid was recrystallized from methanol/ethyl acetate to give yellow needles (2.96 g, 43%) of the required product as its hydrochloride salt. A sample of this material (500 mg) was neutralised by dissolving with warming in the minimum volume of water/methanol and adding sufficient 10% sodium hydroxide to give a pH of 8. The resulting flocculant precipitate was collected, washed with water and dried to give a pale yellow solid (408 mg, 94%) which was recrystallized from ethyl acetate/methanol to give the title compound as the free base, m.p. 280-282 C. (decomposition). (Found: C, 66.13; H, 4.28; N, 27.81. C14 H11 N5.0.25H2 O requires C, 66.26; H, 4.57; N, 27.59%).
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 94220-38-9, 7-Chloro-5-methyl-1H-pyrazolo[4,3-b]-pyridine.
Reference:
Patent; Beecham Group p.l.c.; US4576952; (1986); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem