Related Products of 74115-13-2, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 74115-13-2, name is 5-Bromo-3-pyridinol. This compound has unique chemical properties. The synthetic route is as follows.
To a stirred solution of 1-TERT-BUTOXYCARBONYL-2 (S)-pyrrolidine (2 g, 10 mmol) and 3-bromo-5- hydroxypyridine (1. 57 g, 9.0 mmol), and PPh3 (3.4 g, 13 mmol) in THF (100 mL) was slowly added DEAD (2.05 ML, 13 MMOL). The reaction mixture was stirred at room temperature for 20 h, and concentrated in vacuo. The residue was purified by chromatography with hexane-EtOAc (5: 1) to give a syrup (2.6 g, 81%), [A] D =-52.7 (c 1.1, CHC13). TH NMR (CDC13) 8 8.27 (s, 1H), 8. 25 (d, 1H, J= 2.4 Hz), 7.41 (m, 1H), 4. 20-4. 38 (M, 3H), 3.50-3. 20 (M, 2H), 2.10-1. 80 (M, 4H), 1.47 (s, 9H); 13C NMR (CDC13) 8 155.37, 154.70 and 154.56, 143.12 and 142. 87, 136.74 and 136.39, 123.86, 120.35, 80.01 and 79.64, 69.00 and 68. 71,55. 87 and 55. 58, 46.96 and 46.61, 28.50, 28.04, 23.85 and 22.84.
According to the analysis of related databases, 74115-13-2, the application of this compound in the production field has become more and more popular.
Reference:
Patent; GEORGETOWN UNIVERSITY; WO2005/806; (2005); A2;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem