A new synthetic route of 823-56-3

Statistics shows that 823-56-3 is playing an increasingly important role. we look forward to future research findings about 2-Fluoro-3,5-dichloropyridine.

The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 823-56-3, name is 2-Fluoro-3,5-dichloropyridine. This compound has unique chemical properties. The synthetic route is as follows. 823-56-3

5.0Og (0.030 mol) of 3,5-dichloro-2-fluoropyridine and 5.01g of 1-(1- cyclohexen-l-yl)pyrrolidine (0.033 mol) are stirred neat together at room temperature for Ih and are left at room temperature overnight. The reaction mixture is quenched with 40ml of sulfuric acid 2M. Water is added to the reaction mixture (100 ml) which is extracted thrice with ethyl acetate (50 ml). The combined organic phases are washed with water (150 ml) and brine (100 ml). After separation, the organic phase is dried over magnesium sulfate filtered, concentrated to dryness and purified on silica gel to yield to 0.22 g of 2-[3,5-dichloro-2-pyridinyl]cyclohexanone

Statistics shows that 823-56-3 is playing an increasingly important role. we look forward to future research findings about 2-Fluoro-3,5-dichloropyridine.

Reference:
Patent; BAYER CROPSCIENCE SA; WO2006/122952; (2006); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem