The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 846036-96-2, name is (4-Amino-6-chloropyridin-3-yl)methanol. This compound has unique chemical properties. The synthetic route is as follows. COA of Formula: C6H7ClN2O
Scheme 8 compound 4 (600 mg, 3.77 mmol) was dissolved in THF (50 mL). To this solution was added Mn02 (3.32 g, 37.7 mmol) in one portion. The resulting mixture was stirred at RT for 5 h. TLC showed the reaction completed. The solid Mn02 was filtered out. The filtrate was concentrated to give compound 5 (3.7 g, yield: 86.5%>) as a white solid.
With the rapid development of chemical substances, we look forward to future research findings about 846036-96-2.
Reference:
Patent; MANNKIND CORPORATION; TOLERO PHARMACEUTICALS, INC.; ZENG, Qingping; FARIS, Mary; MOLLARD, Alexis; WARNER, Steven L.; FLYNN, Gary A.; WO2014/52365; (2014); A1;,
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