Reference of 936841-69-9, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 936841-69-9, name is 4-(Trifluoromethyl)picolinonitrile. This compound has unique chemical properties. The synthetic route is as follows.
To a solution of 4-(trifluoromethyl)pyridine-2-carbonitrile (500 mg, 3.0 mmol) in 10 ml ethanol was added hydroxylammonium chloride (302 mg, 4.0 mmol) and triethylamine (382 mg, 4.0 mmol) and then the reaction mixture was stirred 13 h at 50 C. After cooling to RT, the solvent was evaporated and the crude was solved in dichloromethane and extracted with water. The organic phase was dried over magnesium sulfate, filtered and evaporated under vacuum to yield the title compound (432 mg, 65 % of theory, 90 % purity). The compound was used without further purification. LC-MS (method 2B): RT = 1.78 min, m/z = 206 (M+H)+
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 936841-69-9, 4-(Trifluoromethyl)picolinonitrile.
Reference:
Patent; BAYER PHARMA AKTIENGESELLSCHAFT; ELLERMANN, Manuel; VALOT, Gaelle; CANCHO GRANDE, Yolanda; HAssFELD, Jorma; KINZEL, Tom; KOeBBERLING, Johannes; BEYER, Kristin; ROeHRIG, Susanne; SPERZEL, Michael; STAMPFUss, Jan; MEYER, Imke; KOeLLNBERGER, Maria; BURKHARDT, Nils; SCHLEMMER, Karl-Heinz; STEGMANN, Christian; SCHUHMACHER, Joachim; WERNER, Matthias; HEIERMANN, Joerg; HENGEVELD, Willem Jan; (764 pag.)WO2016/71216; (2016); A1;,
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