Abe, Aki M. M.; Sauerland, Sami J. K.; Koskinen, Ari M. P. published an article in Journal of Organic Chemistry. The title of the article was 《Highly Enantioselective Conjugate Addition of Thiols Using Mild Scandium Triflate Catalysis》.SDS of cas: 410092-98-7 The author mentioned the following in the article:
A Sc complex of the bis[(4S,5S)-diphenyloxazolinyl]pyridine I, diphenyl-PYBOX, catalyzed the asym. conjugate addition reactions between thiols and 3-crotonoyl-2-oxazolidinone to give the corresponding adducts, e.g. butanoyloxazolidine II, in good yields and high enantioselectivity (up to 92% ee). A new improved method for making (4S,5S)-diphenyl PYBOX was presented. The experimental part of the paper was very detailed, including the reaction process of 2,6-Bis((4S,5S)-4,5-diphenyl-4,5-dihydrooxazol-2-yl)pyridine(cas: 410092-98-7SDS of cas: 410092-98-7)
2,6-Bis((4S,5S)-4,5-diphenyl-4,5-dihydrooxazol-2-yl)pyridine(cas: 410092-98-7) belongs to pyridine derivatives. Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals. SDS of cas: 410092-98-7