Agin, Fatma published the artcileElectroanalytical Methods for Determination of Calcium Channel Blockers, Application of 3-Ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate, the main research area is review serum calcium channel blocker differential pulse voltammetry.
Background: Calcium Channel Blockers (CCBs) are widely used in the treatment of cardiovascular and ischemic heart diseases in recent years. They treat arrhythmias by reducing cardiac cycle contraction and also benefit ischemic heart diseases. Electroanal. methods are very powerful anal. methods used in the pharmaceutical industry because of the determination of therapeutic agents and/or their metabolites in clin. samples at extremely low concentrations (10-50 ng/mL). The purpose of this review is to gather electroanal. methods used for the determination of calcium channel blocker drugs in pharmaceutical dosage forms and biol. media selected mainly from current articles. Methods: This review mainly includes recent determination studies of calcium channel blockers by electroanal. methods from pharmaceutical dosage forms and biol. samples. The studies of calcium channel blockers electroanal. determination in the literature were reviewed and interpreted. Results: There are a lot of studies on amlodipine and nifedipine, but the number of studies on benidipine, cilnidipine, felodipine, isradipine, lercanidipine, lacidipine, levamlodipine, manidipine, nicardipine, nilvadipine, nimodipine, nisoldipine, nitrendipine, diltiazem, and verapamil are limited in the literature. In these studies, DPV and SWV are the most used methods. The other methods were used less for the determination of calcium channel blocker drugs. Conclusion: Electroanal. methods especially voltammetric methods supply reproducible and reliable results for the anal. of the analyte. These methods are simple, more sensitive, rapid and inexpensive compared to the usually used spectroscopic and chromatog. methods.
Current Analytical Chemistry published new progress about Blood analysis. 72509-76-3 belongs to class pyridine-derivatives, name is 3-Ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate, and the molecular formula is C18H19Cl2NO4, Application of 3-Ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate.