《Using fluoroform for constructing aromatic and heterocyclic trifluoromethylselenyl compounds》 was written by Aharon, Cheryl; Rozen, Shlomo. SDS of cas: 197958-29-5This research focused ontrifluoromethylselenium compound preparation; aromatic selenium cyanide trifluoromethyl copper trifluoromethylation; heterocyclic selenium cyanide trifluoromethyl copper trifluoromethylation. The article conveys some information:
Fluoroform is used to prepare CuCF3 according to literature procedures. This nucleophilic trifluoromethyl moiety was reacted with aromatic and heterocyclic selenium cyanide derivatives 3-R-4-N(R1)(R2)-5-R3C6H2SeCN (R = H, Me, Br; R1 = H, Et, Ac; R2 = H, Et, Ac; R3 = H, Me), 3-R4-4-R5-C6H3SeCN (R4 = H, Me; R5 = Me, t-Bu, Cl, etc.), I (R6 = H, Br; R7 = H, SeCN; R8 = H, SeCN) and II (X = O, S) resp. to form the corresponding trifluoromethylselenium compounds 3-R-4-N(R1)(R2)-5-R3C6H2SeCF3, 3-R4-4-R5-C6H3SeCF3, III (R9 = H, SeCF3; R10 = H, SeCF3) and IV. Selenium cyanides were made with 1,3-dicyanotriselenide prepared in situ from malononitrile and selenium dioxide. The electrophilicity of the reagent (δ+SeCN) was enough to attack aniline derivatives 3-R-4-N(R1)(R2)-5-R3C6H3 at the para position, but with other aromatics it was advantageous to use the corresponding boronic acids 3-R4-4-R5-C6H3B(OH)2, V (R11 = H, B(OH)2; R12 = H, B(OH)2) and VI as the moiety was easily displaced by the selenium cyanate moiety. In addition to this study using 2-Pyridinylboronic acid, there are many other studies that have used 2-Pyridinylboronic acid(cas: 197958-29-5SDS of cas: 197958-29-5) was used in this study.
2-Pyridinylboronic acid(cas: 197958-29-5) belongs to pyridine. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Additionally, pyridine-based natural products continue to be discovered and studied for their properties and to understand their biosynthesis.SDS of cas: 197958-29-5