On January 17, 2019, Ahmad, Nadia; Anderson, Corey; Arumugam, Vijayalaksmi; Asgian, Iuliana Luci; Camp, Joanne Louise; Fanning, Lev Tyler Dewey; Hadida Ruah, Sara Sabina; Hurley, Dennis; Schmidt, Yvonne; Shaw, David; Sheth, Urvi Jagdishbhai; Thomson, Stephen Andrew published a patent.Recommanded Product: Methyl 5-amino-4-methylpicolinate The title of the patent was Preparation of (hetero)aromatic carboxamides as modulators of sodium channels for the treatment of diseases. And the patent contained the following:
The invention relates to preparation of aryl heteroaryl carboxamides and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels. The example compound I was prepared by multistep synthesis (procedure given). Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain. The experimental process involved the reaction of Methyl 5-amino-4-methylpicolinate(cas: 868551-99-9).Recommanded Product: Methyl 5-amino-4-methylpicolinate
The Article related to aryl heteroaryl carboxamide preparation sodium channel modulator disease treatment, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Amides, Amidines, Imidic Esters, Hydrazides, and Hydrazonic Esters and other aspects.Recommanded Product: Methyl 5-amino-4-methylpicolinate