Akishina, E. A.; Dikusar, E. A.; Stepin, S. G.; Alekseyev, R. S.; Bumagin, N. A.; Potkin, V. I. published an article in 2022. The article was titled 《Synthesis of 4-Acetyl- and 4-Benzoylpyridine Derivatives with 1,2-Azole Fragments》, and you may find the article in Russian Journal of General Chemistry.Safety of 4-Acetylpyridine The information in the text is summarized as follows:
A method for the synthesis of 5-arylisoxazole- and 4,5-dichloroisothiazole-3-carboxylic acids derivatives I (R1 = H, Me, Ph; R2 = H, Cl; R3 = Cl, Ph, 4-methylphenyl, 4-nitrophenyl; X = S, O) based on 4-acetyl- and 4-benzoylpyridine has been developed. Esters I and amides II were prepared by acylation of (pyridin-4-yl)methanols III (R4 = OH) and (pyridin-4-yl)methanamines III (R4 = NH2) with acid chlorides of substituted 1,2-azole-3-carboxylic acids IV in ether or methylene chloride in the presence of triethylamine. Quaternary ammonium salts V of synthesized pyridine derivatives were also obtained. In the experiment, the researchers used many compounds, for example, 4-Acetylpyridine(cas: 1122-54-9Safety of 4-Acetylpyridine)
4-Acetylpyridine(cas: 1122-54-9) belongs to pyridine. Pyridine and its simple derivatives are stable and relatively unreactive liquids, with strong penetrating odours that are unpleasant.Safety of 4-Acetylpyridine