Rhodium-Catalyzed Selective Mono- and Diamination of Arenes with Single Directing Site “On Water” was written by Ali, Ashif Md;Yao, Xiayin;Li, Guigen;Lu, Hongjian. And the article was included in Organic Letters in 2016.Recommanded Product: 4373-61-9 This article mentions the following:
A Rh(III)-catalyzed selective C-H amination of 2-phenylpyridine derivatives is reported. With pyridine as a directing group, the reaction has high mono- or diamination selectivity, and a wide range of effective substrates, including electron-deficient and -rich aryl azides. Water helps to promote C-H activation, and the concept of a water-promoted rollover mechanism is postulated for the diamination step. The reactions were conducted using a Schlenk flask and proceeded smoothly “on water” under atm. conditions with nitrogen gas as the only byproduct. In the experiment, the researchers used many compounds, for example, 2-(m-Tolyl)pyridine (cas: 4373-61-9Recommanded Product: 4373-61-9).
2-(m-Tolyl)pyridine (cas: 4373-61-9) belongs to pyridine derivatives. Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. The standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.Recommanded Product: 4373-61-9