Amino, Yusuke published the artcileNovel method for the synthesis of 2′,3′-unsaturated nucleosides from 2′(3′)-acetoxy-3′(2′)-halogeno derivatives by using sodium dithionite with viologen as a reductive elimination mediator, Safety of 1,1-Di-n-octyl-4,4-bipyridinium Dibromide, the main research area is viologen mediated reductive elimination acetylbromodeoxy nucleoside; unsaturated dideoxy nucleoside.
Reductive elimination of vicinal acetylated halohydrins with Na2S2O4 as the reducing agent and viologen as the reduction mediator in a 2-phase water-organic system is described. 2′,3′-Unsaturated nucleosides such as 1-(5-O-acetyl-2,3-dideoxy-β-D-glycero-pent-2-enofuranosyl)adenine (I), -hypoxanthine, and -uracil were obtained from 2′(3′)-acetoxy-3′(2′)-halogeno derivatives, e.g., II, in good yields by means of this procedure.
Chemical & Pharmaceutical Bulletin published new progress about Nucleosides Role: RCT (Reactant), RACT (Reactant or Reagent). 36437-30-6 belongs to class pyridine-derivatives, name is 1,1-Di-n-octyl-4,4-bipyridinium Dibromide, and the molecular formula is C26H42Br2N2, Safety of 1,1-Di-n-octyl-4,4-bipyridinium Dibromide.