An article Fluorenone Schiff base derivative complexes of ruthenium, rhodium and iridium exhibiting efficient antibacterial activity and DNA-binding affinity WOS:000525896700010 published article about METAL-COMPLEXES; LIGANDS in [Kollipara, Mohan Rao; Shadap, Lathewdeipor] North Eastern Hill Univ, Ctr Adv Studies Chem, Shillong 793022, Meghalaya, India; [Banothu, Venkanna] JNTUH, Ctr Biotechnol CBT, IST, Hyderabad 500085, Telangana, India; [Agarwal, Nipanshu; Poluri, Krishna Mohan] Indian Inst Technol Roorkee, Dept Biotechnol, Roorkee 247667, Uttar Pradesh, India; [Agarwal, Nipanshu; Poluri, Krishna Mohan] Indian Inst Technol Roorkee, Ctr Nanotechnol, Roorkee 247667, Uttar Pradesh, India; [Kaminsky, Werner] Univ Washington, Dept Chem, Seattle, WA 98195 USA in 2020.0, Cited 37.0. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1. Computed Properties of C12H9NO
Metal precursors [(arene)MCl2](2) (arene = p-cymene, Cp*; M = Ru, Rh and Ir) on reacting with 9-fluorenone derivative ligands L1, L2 and L3 resulted in the formation of mononuclear bidentate cationic N boolean AND N bonded complexes. The biological studies of these complexes such as antibacterial activity studies (against Gram-positive and Gram-negative bacteria) revealed significant antibacterial activity with complexes 4, 7 and 9 having the highest activity potency (in-vitro). Whilst for DNA-binding studies, the results revealed that complexes 4 and 5 displayed significant changes in their spectral features upon addition of SM-DNA, thus, indicating that these complexes bind to DNA with a significant affinity. (C) 2020 Elsevier B.V. All rights reserved.
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Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem